As we age, we all want to look and feel younger and enjoy life the way we once did, without all of the excess weight, fatigue, and exhaustion. Many of us have tried to do the things experts advise like eating right, exercising, and getting plenty of rest. Still, we find we need support when critical hormone levels begin to decrease with age. By supplementing the body’s natural ability to produce Human Growth Hormone with Sermorelin injections, we can begin to regain the energy and vitality we once had and start living again, the way we deserve.
What is Sermorelin?
Sermorelin acetate is a Growth Hormone Releasing Hormone (also known as GHRH and GRF 1-29) naturally produced in the brain and necessary to stimulate Growth Hormone (GH). Sermorelin is most commonly used to treat growth hormone deficiency, and for anti-aging purposes. The peptide analogue is considered a secretagogue for its ability to stimulate the pituitary gland to release growth hormone. Sermorelin acetate contains 29 amino acids and as a portion of endogenous human GHRH is also the shortest synthetic peptide for fully functional GHRH activity.
The History of Sermorelin
In the early 1980’s researchers began testing Growth Hormone Releasing Hormone, GHRH. In particular, GHRH was researched to determine which component was necessary to produce a pituitary gland response.
It was found that therapeutic doses of Sermorelin increased amounts of growth hormone secreted by the stimulated pituitary gland. In short, scientists agreed that Sermorelin was useful in the possible diagnoses of GH deficiency, and that GH insufficiency could be successfully managed with subcutaneous injections of the hormone. Marketed under the trade name, “Geref” in 1997 The U.S. Food and Drug Administration approved the use of synthetic Sermorelin as a diagnostic tool, (and shortly thereafter) as a GH therapy.
Benefits of Sermorelin—Alternative to HGH
Growth hormone, secreted by the pituitary gland is converted by the liver into IGF-1 (insulin-like growth factor) at a later time. This increase in IGF-1 benefits the body in a number of ways.
Body composition changes–As we age and HGH levels diminish, a decrease in lean body mass occurs. There is also a marked increase in body fat production at this time. Balancing HGH levels reverses this trend, promoting lean muscle mass and fat reduction.
Bone Mineral Density—HGH deficiency often results in a decrease in bone density. This leads to osteoporosis. By prompting HGH production for just 12 months, there is substantial improvement in bone mineral density.
Muscle Strength—Muscles are weakened as body composition changes. Therapy to stimulate HGH production helps overall muscle strength.
Joint Health—HGH replacement therapy can help prevent joint deterioration as we age. By promoting healthy connective tissue, as well as increased bone mineral density and muscle mass, joint health can be improved.
Enhanced Physical Performance—Reduction in oxygen uptake, decreased bone density and diminished muscle mass all contribute to a lack of physical performance when exercising. Stimulating the production of HGH can help.
Heart Health—Deficiency in growth hormone increases the risk of plaque build up in the arteries. This in turn increases the risk of heart attack or stroke in aging individuals.
Metabolism—Growth hormone affects the resting metabolism. Increased protein synthesis, fat oxidation, a reduction in bad LDL, and the normalization of carbohydrate metabolism occurs with greater GH production.
Skin health—As we age and become deficient in growth hormone, all important collagen levels are reduced as well. This causes skin to become thinner, to sag, and to wrinkle.
Immune function—Evidence suggests that HGH can work to help regulate the body’s stressed and diminished immune function.
Sex Drive—Growth hormone deficiency is related to lower libido and diminished energy levels. HGH production can help restore vitality once again.
Quality of Life—HGH therapy has been linked to increased energy levels, mood improvement, and overall feelings of health and well-being.
Better Sleep Quality—Sermorelin promotes deeper, more rejuvenating sleep. Because HGH is mostly produced at this time, the secretagogue further supports natural Human Growth Hormone production.
Why Sermorelin over HGH
Because HGH deficiency leads to a breakdown in many functions within the body as we age, increasing human growth hormone levels can work to slow or eliminate many of the health related consequences. Treatment with HGH replacement therapy may not be necessary, available, or feasible however. Cost and lack of local resources could put HGH out of reach for some of us.
Sermorelin that actually stimulates the natural production of HGH by the pituitary gland may be all that is needed to support the aging process.
Sermorelin is known for:
- Natural secretagogue capabilities
- Legality (with a prescription for anti-aging purposes)
- Lower cost
- HGH production (even after therapy stops)
Advantages of Sermorelin over HGH
In terms of safety, Sermorelin does not carry some of the adverse side effects such as, diabetes, cancer, and abnormalities with tissue or bone growth. Over medication, or a sudden reduction in HGH response is not a risk with Sermoralin use. Because the body naturally produces growth hormone, synthetic HGH is not necessary.
Possible Side Effects
These may include headache, nausea, vomiting, unusual taste in the mouth,
facial redness and soreness, swelling, or itching at the injection site.
Where to Buy Sermorelin
Accessibility—While Sermorelin is not considered a controlled substance, it is categorized as a pharmaceutical that requires a prescription from a licensed healthcare provider. Because Sermorelin is a secretagogue that only supports natural production of HGH from the pituitary gland, many of the health risks associated with HGH therapy do not exist. As a result, many physicians reluctant to prescribe Human Growth Hormone for anti-aging purposes are willing to offer Sermorelin to patients. Natural wellness clinics, private physicians, and Internet holistic health sites offer access to Sermorelin to slow the aging process.
As we age, our ability to live quality, productive lives is deeply affected by our physical and mental health. Maintaining the body and mind is crucial to overall feelings of well being. Sermorelin injections can help by stimulating the body’s natural ability to produce Human Growth Hormone, which promotes increased strength, greater energy, and a faster metabolism.
1Losa, M., Schopohl, J., Müller, O. and Werder, von (1984) ‘Stimulation of growth hormone secretion with human growth hormone releasing factors (GRF1-44, GRF1-40, GRF1-29) in normal subjects’, Klinische Wochenschrift., 62(23), pp. 1140–3.
2pmhdev (2016a) ‘Sermorelin (by injection) – national library of medicine – PubMed health’, .
3pmhdev (2016b) ‘Sermorelin (by injection) – national library of medicine – PubMed health’, .
4Walker, R.F. (2006) ‘Sermorelin: A better approach to management of adult-onset growth hormone insufficiency?’, 1(4).